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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

PYRAZOLE: SYNTHESIS, REACTION AND BIOLOGICAL ACTIVITY

Shankarsing Sardarsing Rajput*, Sureshbhai Narasaibhai Patel,
Sandip Balu Chaudhari

Abstract

This review summarizes the synthetic methods, reactions and biological application of pyrazole and summarizes recent developments in their derivatives such as formyl pyrazole, Schiff base, chalcone, Aromatic nucleophilic substitutation etc. over the last 10 years. Formation of Pyrazole and fused heterocyclic pyrazole derivatives constitute an interesting class of heterocycles, which have diverse biological activities. The biological activity of the pyrazole is also briefly discussed.

Keywords: Pyrazole, biological activity, Pyrazolopyridine heterocycle, Schiff base, chalcone.

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