Abstract

A COMPARATIVE EVALUATION OF ANTI-CANCER EFFECT OF PANCHGAVYA AND PANCHGAVYAGHRITA BY LEWIS LUNG CARCINOMA CELL LINE IN VITRO STUDY

Yogesh Desai*, Rekha Parmar**, Priya Desai*** and Rutvi Vaidya****

.

Abstract

The study is conducted to explore utilization of Panchgavya and Panchgavyaghrita involved in possible therapeutic application of cow product which is used traditionally for various conditions. In the present study cytotoxicity assay method was carried out to identify the effect of Panchgavya and Panchgavyaghrita as potent anticancer agent in treatment of lung cancer induced by LLC cell line. The test was conducted using MTT dyeand Lewis Lung Carcinoma cell line for invitro characterization of cow product, comparison was done against Doxorubicin as standard cytotoxic drug. Inhibition of cancer cell growth (50%)was found at 7.75 mg/ml of Panchgavya and 6.78 mg/ml of Panchgavyaghrita, for doxorubicin it was found at 1.087×10-10 mg/ml.

Keywords: Panchgavya, Panchgavyaghrita, Lewis Lung Carcinoma, MTT assay, Anticancer activity.