Abstract

COMPUTATIONAL STRUCTURAL AND FUNCTIONAL ANALYSIS OF SHORT NEUROPEPTIDE F FROM TRIBOLIUM CASTANEUM.

*Somnath Waghmare, Manjit Singh Arora, Anant Sherkhane and Viren Gomase

Abstract

In the present study annotating and analysing the function of neuropeptide F from Tribolium castaneum is done. The Tribolium castaneum which is a cosmopolitan pest of stored products. Sequence of Neuropeptide F protein was retrieved from Uniprot and analysed for their structural and functional characteristics by using various bioinformatics tools and database. Subcellular localization prediction suggested that it is a cytoplasmic protein. Furthermore, it was discovered that Neuropeptides and neuro hormones are among the more diverse and functionally important classes of cell-to-cell signaling molecules involved in animal development and behavior. Less is known about the hormones and neuropeptides F of the red flour beetle, Tribolium castaneum, than many other insects. The secondary structural prediction of those proteins has been done which would be useful for further analysis of this protein.

Keywords: Tribolium, Neuropeptide F, Secondary structure, etc.