Abstract

PHARMACOLOGICAL EVALUATION OF WOUND HEALING ACTIVITY ON METHANOLIC EXTRACT OF ANAPHALIS LAWII (HOOK.F) GAMBLE

K.Yamini*, V.Gopal, R.Suthakaran

Abstract

The aim of the study is to evaluate the wound healing activity of methanolic leaf extract of of Anaphalis lawii was studied respectively on two types of wound models in rats, (i) the excision and (ii) the incision wound model. The methanolic extract of Anaphalis lawii leaves produced significant response in both of the wound types tested. In the excision model the extract treated wounds were found to epithelialise faster and the rate of wound contraction was higher, as compared to control wounds. The extract facilitates the healing process as evidenced by increase in the tensile strength in the incision model. The results were also comparable to those of a standard drug Framycetin.

Keywords: Wound healing, Incision model, Excision model, Anaphalis lawi leaves.