Abstract

A REVIEW-NANOPARTICULATE ANTICANCER TARGETED DRUG DELIVERY SYSTEM

Nikhil Prabhakar Patil* and Dr. Kiran Sanjay Bhise

Abstract

Nanoparticles have critical advantage in the treatment of cancer and the inherent leaky vasculature present serving cancerous tissues. The strategy for targeting the tumor vasculature can allow targeted delivery to a wide range of tumor types. Hence considering the importance of treating cancer, an attempt will be made to target and deliver an anticancer drug to these cancerous cells so as to minimize adverse effects, dose and also dosing frequency. This is achieved by formulating anticancer drugs in the form of nanoparticles. The importance and necessity of nano based formulation was discussed with the help of giving present situation in cancer world, their study based review on the basis of scientific data and patent across different countries. The present review gives an idea about formulation development for specific tumour targeting of cells causing cervical cancer, their method of preparation and characterization study.

Keywords: Lipid Nanosphere, Formulation Optimization, Characterization.