PRINCIPLE, FORMULATION, CHARACTERIZATION AND APPLICATION OF NANOFIBERS IN PHARMACEUTICALS-A REVIEW
Rabiya Patel* and Swati Deshmukh
.
Abstract
Conventional oral dosage forms exhibit poor/low bioavailability due to
incomplete release of drug and short residence time at the absorption
site. The benefits of the fibrous carriers are site specific delivery of
drugs to the body. Nanofibers are an exciting new class of material
produced using an innovative manufacturing process technology. At
present, there are three techniques available for the synthesis of
Nanofibers: Electro spinning, self-assembly, and phase separation, out
of these Electro spinning is the most widely used technique.
Electrospinning has been recognized as an efficient technique for the
fabrication of polymer nanofibers. Various polymers have been successfully electrospun into
ultrafine fibers in recent years mostly in solvent solution and some in melt form. In this
article, we discussed principle, process of manufacturing, characterization, application of
nanofibers.
Keywords: Nanofiber, Electrospinning, Tissue engineering etc.
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