Abstract

PRINCIPLE, FORMULATION, CHARACTERIZATION AND APPLICATION OF NANOFIBERS IN PHARMACEUTICALS-A REVIEW

Rabiya Patel* and Swati Deshmukh

Abstract

Conventional oral dosage forms exhibit poor/low bioavailability due to incomplete release of drug and short residence time at the absorption site. The benefits of the fibrous carriers are site specific delivery of drugs to the body. Nanofibers are an exciting new class of material produced using an innovative manufacturing process technology. At present, there are three techniques available for the synthesis of Nanofibers: Electro spinning, self-assembly, and phase separation, out of these Electro spinning is the most widely used technique. Electrospinning has been recognized as an efficient technique for the fabrication of polymer nanofibers. Various polymers have been successfully electrospun into ultrafine fibers in recent years mostly in solvent solution and some in melt form. In this article, we discussed principle, process of manufacturing, characterization, application of nanofibers.

Keywords: Nanofiber, Electrospinning, Tissue engineering etc.