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Abstract

A EMERGING CONCEPT: FLOATING DRUG DELIVERY SYSTEM

Swami Shubhangi M.*, Wakchaure Varsha S., Tilekar Devika K. and More Archana S.

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Abstract

The purpose of writing this review on floating drug delivery system was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. This review entitled the detailed scenario related to floating drug delivery system with their advantages over conventional drug delivery system and limitation which are helpful in development of dosageform. This triggered an increased interest towards formulation of novel delivery systems which retained in stomach for prolonged and predictable period of time. The several approach are currently utilized in the prolongation of the gastric retention time, including floating drug delivery system also known as hydrodynamically balance system, swelling and expanding system, polymeric bioadhesive systems, modified shape systems, high density systems and other delayed gastric emptying devices. From the formulation and technological point of view the floating drug delivery system is considerable easy and logical approach. This review article is in pursuit of giving detailed information on the pharmaceutical basis of their design, classification, advantages, in vitro and in-vivo evaluation parameters and the future potential of floating drug delivery system. An attempt has been made in this review article to introduce the readers to the current technological development in floating drug delivery system.

Keywords: Gastro Retentive drug delivery system.


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