Abstract

AN AYURVEDIC APPROACH OF DUCHENNE MUSCULAR DYSTROPHY - A BRIEF REVIEW

Sakshi Vijay Kadam* and Bahuraj Janagond

Abstract

Duchenne muscular dystrophy (DMD) is the most common hereditary neuromuscular disease in Indian children affecting all races and ethnic groups. It is a X-linked recessive trait. The abnormal gene is Xp21 locus and is one of the largest genes. Connection of extracellular matrix (ECM) to the cell cortex of muscle and non-muscle cells. ECMCell cortex association important for cell strength. Loss of Dystrophin makes cells fragile. Muscle cell and muscle fibres degenerate. Its characteristic clinical features are progressive muscle weakness of mainly proximal lower limb muscles, intellectual impairment, proliferation of connective tissue in muscle, hypertrophy of calves. In Ayurvedic approach it can be classified under Adibalpravrittavyadhi. Pathogenesis occurs due to Beejbhaga Avayavadushti due to which vataprakopa takes place (sthansamshraya) at medomamsadhatu and deplete them. There is no curative treatment to DMD in modern science but according to Ayurveda, Panchkarma, Rasayana, are the important therapy in this disease. Ayurveda do not proclaim as curative but can be use to improve the quality of life of DMD patients.

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