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Abstract

Antimicrobial potential of Erigeron floribundus extracts against some aquatic bacteria of sanitary importance: influence of pH

Luciane Marlyse Moungang*, Roland Ndifor Ache, Olive Vivien Ewoti Noah, Blaise Lambou Fometio, Hervé Narcisse Bayaga, Antoine Arfao Tamsa, Mouhama Sani Adams Ibn Rabiou and Moïse Nola

Abstract

Nowadays, humans suffer from many infectious water borne diseases such as gastro-enteritis, cholera and typhoid fever. Antibiotics that have been used for several decades to limit disease phenomena are increasingly losing their effectiveness due to their excessive and uncontrolled use. Hence, necessitates alternative treatments, including plant derived remedies. The aim of this study was to evaluate the aqueous and ethanolic leaves extract of Erigeron floribundus on three important sanitary bacteria (Escherichia coli, Staphylococcus aureus and Enteroccoccus feacalis) with a variation of the pH medium. Escherichia coli, Staphylococcus aureus and Enteroccoccus feacalis were isolated from well water in the city of Yaounde. The qualitative phytochemical screening was conducted using colorimetric precipitation methods. The pH of the medium was adjusted using a pH meter, HCl and NaOH solutions. The antimicrobial activities were evaluated by the surface spreading on agar medium, membrane filter technique and microdilution methods. The phytochemical screening of both extracts revealed in common the presence of alkaloids, saponins, polyphenols and tannins. Cardiac glycosides, flavonoids, resins, quinones and mucilages were only present in the ethanolic extract. With the exception of Enterococcus feacalis, the bacterial strains were more sensitive to the ethanolic extract compared with the aqueous extract; and the minimum inhibitory concentration (MIC) values ranges from 3.12 to 25 mg/mL. Statistical analyses showed no significant correlation between bacterial abundance and extract concentration at various pH range. Conclusively, the aqueous and ethanolic extracts of the leaves of Erigeron floribundus, have secondary metabolites with antibacterial activity; therefore, justifying the use of Erigeron floribundus, as disinfectant and for the treatment of some water borne diseases.

Keywords: Water, phytochemical screening, Erigeron floribundus extracts, antibacterial activity.


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