Abstract

PROTECTIVE EFFECT OF POLYBION AGAINST RADIATION AND CADMIUM INDUCED CHANGES IN ACID PHOSPHATASE CONTENT IN THE LIVER OF SWISS ALBINO MICE

Ramesh Kumar Purohit*

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Abstract

Man has always been exposed to ionizing radiation from natural sources. The natural background exposure varies with the locations. No ill effects have been uniquely correlated. Either no deleterious effects are produced at these levels of exposure or their frequency is too low to be statistically observable. Direct source of information on radiation hazards in man is obviously based on follow up of population groups exposed to certain levels of radiation. Harmful effects of ionizing radiations recorded from exposed radiologists during 1920s and 30s, miners exposed to airborne radioactivity, workers in the radium industry, follow-up data of Japanese nuclear bomb survivors of Hiroshima and Nagasaki, the Marshallese accident in 1954, and the victims of the limited number of accidents at nuclear installations including Chernobyl form the basis of data to develop various recommendations. From these various sources, the pattern of events that follows a total body exposure to a dose of ionizing radiation have been well documented. Mostly this information is from situations involving higher doses and dose rates. In the present study biochemical parameters of acid phosphatase and alkaline phosphatase have been taken under consideration.

Keywords: Polybion, Radiation hazards, Acid phosphatase cadmium chloride.