Abstract

DEVELOPED INSTRUMENTAL EXPLORATION AND ASSESSMENT OF SIDDHA FORMULATION ELADHI CHOORANAM

Dr. R. Tamilselvan*, P. Gnanavel, K. Bharathi and Saravanadevi M. D.

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Abstract

The main aim of the present investigation is to identify the functional group of Siddha formulation Eladhi Chooranam (EC) by FT-IR and also characterize the same by using sophisticated techniques like SEM and XRD. The information’s obtained from the present analysis offers valuable information with respect to surface morphological features of the Siddha formulation EC with the size range of 5-1micron. FT-IR analysis of the sample EC reveals the presence of 9 prominent absorption peaks. Further it evident the presence of peaks corresponds to presence of free hydroxyl and phenolic functional group. The major diffraction peaks are identified in XRD analysis of EC shows that the particles are in the average size range of 33-76nm. The Size and surface of micro particles can be easily manipulated to achieve both passive and active drug targeting. They control and sustain the release of drug during the transportation and at the site of localization, alter the drug distribution in the body and subsequent clearance of the drug so as to achieve increased drug therapeutic efficacy there by it increases the bio-availability of the drug and reduced the side effects. Hence, EC which is prepared biologically contains micro particles to enhance the pharmacological action in the target site.

Keywords: Siddha, Eladhi Chooranam, Standardization, FT-IR, SEM, XRD.