Abstract

ANTI-DIABETIC AND WOUND HEALING POTENTIAL OF JASMINUM GRANDIFLORUM

Basavaraj S. Hunasagi* and Shashikant N. Dhole

.

Abstract

The present study describes the anti-diabetic and Wound healing potential of ethanoloic extract of Jasminum grandiflorum Linn. Leaves on streptozocin induced diabetic rats and excision wound model to substantiate its folklore claim. The ethanolic extracts at two doses 100 and 200 mg/kg, p.o. prevented diabetes by Glucose oxidase method further studying its lipid profiles and anti-oxidant effects in rats. The wound healing potential of diabetic rats were confirmed by the excision wound model studies with surface epithelization and wound contraction. Pretreatment with ethanolic extract of Jasminum grandiflorum Linn. leaves significantly (P < 0.05) increased the antioxidant enzymes and lipid peroxidation index. Further in wound healing activity the epithelialization period was significantly (p

Keywords: Anti-diabetic activity, Wound healing activity, ethanol, streptozocin Lipid profile studies, Jasminum grandiflorum Linn. Leaves.