Abstract

IN VIVO STUDY OF IZDIAD-E-GHUDDA-E-IFRAZATH-E-GHUDDAE- DARQIA (HYPERTHYROIDISM) IN ANIMAL EXPERIMENT

Dr. Roohi Khatoon*

Abstract

Background: Thyroid disorders are very common throughout the world. Hyperthyroidism is essentially an autoimmune disease. According to Hakim Najmul Ghani the test drug Brahmi and Badranjboya for the management of GALAGANDA swelling of neck tumour, goitre that can be corelated with the hyperthyroidism is the evident from historical literature of Unani system of medicine. Aim of the study: The present pre –clinical in vivo Study of Brahmi (Centella asiatica) and Badranjboya, (Nepeta hindustana) in the management of drug-induced hyperthyroidism. Material And Methods: The Present pre-clinical study “In vivo study of Izdiad-e- Ifrazath- e-Ghudda-e- Darqia (hyperthyroidism) in Animal experiment” 30 Albino wistar rats (6 Groups, 14 days oral route). Except control group, all the rats were given thyroxine 600 μg /kg/bw Test drug Dose fixation done after toxic study for both drugs, 500mg/kg/bw. Result: Tgc Vs Sg Results T3 Mean Diff 47.33, P Value

Keywords: Brahmi, Badranjboya, Ghudda-e-arqia, Izdiad-e-razath-e-Darqia.