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Abstract

ANTIOXIDANT SCREENING OF SHOREA THUMBUGGAIA ROXB. AN ENDEMIC AND ENDANGERED SPECIES OF SESHACHALLUM HILLS

Dr. R. Vinolya Kumari*

Abstract

Shorea thubuggaia Roxb. belongs to the family Dipterocarpaceae is globally highly threatened and vulnerable medicinal plant. The aim of this study was to assess, antioxidant activity for the first time from different parts of leaves, stem and root of shorea thubuggaia by using stable free radical 1,1Dipheny-2- Picryl Hydrazyl(DPPH), Hydrogen Peroxide (H2O2) and Nitric oxide (NO) Scavenging activity. The plant extracts showed antioxidant effect which is expected mainly due to phenolic components such as flavonoids, phenolic acids and phenolic diterpenes. This phenolic component possesses many hydroxyl groups including O-dihydroxl group which have very strong radical scavenging effect and antioxidant power. In DPPH assay, the antioxidant was able to reduce the stable radical DPPH to yellow colour. The observed scavenging effect of plant extracts and standards on the DPPH radical is very high in leaves at 75μg/ml when compare to stem and root respectively. The DPPH assay provides an easy rapid way to evaluate potential antioxidants. The H2O2 scavenginging activity is also high in leaves when compare to stem and root. The Hydrogen peroxide sometime it can be toxic to living cells, because in living cells it is converted into free radical called hydroxyl radicals(OH), react with biomolecules, causes tissue damage and cell death. Nitric oxide is a potent pleiotropic mediator of physiological processes. Its activity is high in stem and leaf when compare to root. Hence, it can be concluded that S. thumbuggaia could be pharmaceutically exploited for antioxidant properties.

Keywords: Antioxidants, methanolic extract, free radical, DPPH Scavenging.


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