WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

FORMULATION OF ACYCLOVIR TRANSDERMAL GEL USING ALEOVERA AS PENETRATION ENHANCER FOR HERPES TREATMENT

*Dr. Vivek Gupta and Shobha Rajpoot

Abstract

The aim of this study was to investigate the in-vitro permeation enhancement effects of the gel and Aloe vera using acyclovir as a marker compound. Aloevera, acyclovir and Polysorbate 80 were used for preparation of gel. The perepared grl was evaluated for Determination of pH, Determination of Viscosity, Drug Content, Spreadability and In vitro drug release study. Incorporation of penetration enhancer (polysorbate 80) showed modified or improved in-vitro permeability and enhancement of the drug. In the formulation greatest permeation is achieved at 4 % concentration of penetration enhancer (polysorbate 80) and hence S4 can be termed as the best formulation among those that are developed. In the formulation use of aloe vera gel as absorption base it posses soothing, moisturizing and healing properties, aloe vera gel contain of lignins, that allows for penetrative properties.

Keywords: Aloevera, Acyclovir, Transdermal gel, formulation, Penetration enhancer.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More