A REVIEW ON BIOLOGICAL ACTIVITY AND SYNTHETIC METHODS OF ISOINDOLE NUCLEUS
Dr. Sanjay Singh*, Gaurav Kumar, Manisha Negi and Babita Mehra
.
Abstract
Isoindole is one of the most important heterocyclic compound, strong
base than pyrrole, having varied biological activities and still of great
scientific interest at this time. They are extensively found in bioorganic
and medicinal chemistry with application in drug discovery. Isoindole
is a benzo-fused pyrrole. The compound is an isomer of indole.
Nitrogen atom constitutes the core structure of pyrrole and many
pharmacologically and biologically active compounds. Isoindole is
among the usually occurring heterocyclic nuclei in many natural plant
products. Isoindole is known to exhibit a wide range of biological
properties including, anticancer, antimicrobial, antimalarial, antiinflammatory,
antibacterial, antifungal, antitubercular activities.
Keywords: Isoindole, pharmacological activities, antimicrobial activity, anti malarial activity, anti bacterial, antifungal activity.
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