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Abstract

“EFFICACY OF HOMOEOPATHIC MEDICINES IN CASES OF CELIAC DISEASE IN ADOLECENTS WITH THE AID OF HOMOEOPATHIC MEDICAL REPERTORY BY ROBIN MURPHY- AN OPEN LABEL CLNICAL TRIAL.”

*Dr. Yasir Mirza, Dr. Aijaz Aziz Sulemani, Dr. Neetu Singh, Dr. Sudhir Sharma, Dr. Anil Aggarwal and Dr. Rubina Khanam

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Abstract

Background - Celiac disease (CD), also known as gluten-sensitive enteropathy or celiac sprue, is defined as a permanent intolerance to ingested gluten (the storage protein components of wheat, barley and rye. The intolerance to gluten results in immune-mediated damage to the mucosa of the small intestine characteristically inducing villous atrophy and crypt hyperplasia that resolve with the removal of gluten from the diet. Homeopathy can treat celiac disease and individual susceptibility. The right constitutional similimum arrived by the help of mental generals, physical generals, characteristic particulars, causation, modalities and concomitants helps in removing the underlining susceptibility and bring out the cure. It can also managed by diet regimen and life style modification along with homoeopathic treatment. Objectives - To assess the extent of improvement in cases of celiac disease with Homoeopathic medicines by The Gastrointestinal symptom rating scale (GSRS) and lowering the tTG levels. Study Design - An open label clinical trial Methods & Methodology - A total of 60 patients were enrolled in the study meeting the inclusion and exclusion criteria after screening from the hospital OPD. The data of 60 participants, were analyzed after 6 follow ups. In this study, the management of celiac disease began with the assessment of tTG level and severity of symptoms with the help of The Gastrointestinal symptom rating scale (GSRS) and with the aid of Homoeopathic Medical Repertory by Robin Murphy. They were then given homoeopathic intervention through holistic approach and reassessed for symptoms severity. Results - Observations and Results shows that among 60 cases of Celiac Disease enrolled in the study, the age group of 10-21 years was enrolled both males and females. In the study more cases were from urban area residence. Commonly middle class socio-economic status people 68.33%, upper class 18.33% and Lower class 13.33% were affected. 60 Cases of Celiac Disease were treated with individualized Homeopathic medicine on the basis of totality of symptoms as add on treatment. The most frequently prescribed Homoeopathic medicines were Ars. Alb. (n=12), Sulph. (n=9), China (n=8), Ipec.(n=6), Phosphorus (n=6), Lyco (n=5), Puls. (n=4), Podo. (N=3), Acid Nit. (n= 2), Colo. (n=2), bryo.(n=1), Carc. (n=1), Nat.Mur. (n=1), Cal Carb (n=1), Cactus G (n=1), Carbo.V. (n=1), Iris (n=1), Kali.C. (n=1), Nux.V.(n=1), R.T. (n=1), Bell (n=1), Nat.Carb.(n=1), Butyric Acid (n=1). Among 60 cases of Celiac Disease cases were improved and 06 cases were not improved on the basis of biochemical parameters like The Gastrointestinal symptom rating scale (GSRS) and lowering the tTG levels. Conclusion – • Homoeopathic medicines selected on the basis of individualization with aid of Homoeopathic Medical Repertory by Robin Murphy reduce the GSRS as well as tTG levels, which is important in Celiac disease patients for preventing future complications of Celiac Disease. • The most commonly used medicines were Ars. Alb., Sulph., China., Ipec., Phosphorus, Lyco., Puls., Podo., Acid Nit., Colo., Bryo., Carc., Nat.Mur., Cal Carb, Cactus G, Carbo.V., Iris, Kali.C., Nux.V., R.T., Bell, Nat.Carb., Butyric Acid. The present study was a tiny initiative effort in the direction of evidence based studies dealing with Celiac disease through Holistic approach in Homoeopathy and helpful in establishing the significant role of Homoeopathic remedies in managing cases of Celiac disease through Holistic approach with Homoeopathic Medical Repertory by Robin Murphy.

Keywords: Celiac Disease, Adolescents, Homoeopathic Medical Repertory by Robin Murphy, The Gastrointestinal symptom rating scale (GSRS), The tTG levels, Individualized medicine.


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