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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

ARTIFICIAL PANCREAS’ – A GAME CHANGER

S. Dahlia Dixcy*, Dr. P. Sharmila Nirojini, J. Bharathi, A. Asifa Shaz, V. Durga and A. G. Anjana

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Abstract

Type 1 DM is a metabolic disorder characterized by lack of insulin due to complete autoimmune destruction of the pancreas. Hence people with T1DM require intensive insulin therapy as well as glucose monitoring. Obtaining near-normal values of glucose is the main aim of T1DM treatment which still remains unachieved in most of the people with type 1 diabetes in spite of other therapies. Recent research in the field of type 1 diabetes medicinal devices has focused on improving glucose monitoring and insulin delivery devices with the goal of combining them into an artificial pancreas, closed-loop insulin administration system. Artificial pancreas system is a recent medical innovation, which helps to keep glucose levels in check, tackles hypoglycemia and is also said to be effective when compared to other devices. The employment of a control algorithm that controls insulin administration based on real-time sensor glucose readings distinguishes this unique technique from traditional pump therapy. This review is aimed to provide a detailed description about the APS system, it’s working, benefits as well as its downsides.

Keywords: Artificial pancreas, Diabetes Mellitus, Closed-loop systems, Continuous glucose monitoring, Controller, Insulin pumps.


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