Abstract

NANOCOMPOSITES: A PROMISING DRUG DELIVERY IN PHARMACEUTICAL INDUSTRIES

Madhura Satish Chothave*, Aishwarya Chandramore, Vrushali Jagatap and Dr. Kunal V. Bhambar

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Abstract

Nanotechnoloigy is the field of science which deals with the development of materials lesser than the normal size. The field generally, focuses upon nanoscale product development using various methodologies. The size range for such a product lies in between 1 to 100nm scale. Nanocomposite is one of the promising nanotechnological tool which has abundant applications into the pharmaceutical field, tissue engineering, cell culture development, medical devices, cell culture development etc. The issues related with conventional therapeutics like stability, drug toxicity, poor patient compliance, drug delivery associated with the candidates having low solubility, and low permeability, drug resistance into the body are widely taken into consideration. To overcome those problems nanocomposites are designed, developed and produced in modern practice of medical science. They have been developed with the decreased gas, water, hydrocarbon permeability, modified surface properties, thermal stability, mechanical properties like shape & strength, which has high surface-volume ratio and optical clarity. This review will detail the advantages, characteristics, types of nanocomposites also, different techniques used to produce the nanocomposites etc. Briefly the review will focus on the pharmaceutical industrial applications of nanocomposites especially for the targeted drug delivery system.

Keywords: Nanocomposites, Clay-based, Polymer-matrix, Hydrogels, Films, Nanoparticles.