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Abstract

SYNTHESIS AND EVALUATIVE STUDY OF CHALCONES AND THEIR DERIVATIVE FOR ANTI-OXIDANT ACTIVITY

Muizz Kachhi*

Abstract

Background: Chalcones are among the leading categories of flavonoids across the entire kingdom of plant, The term chalcone is originated from the Greek name chalcos which means bronze. Chalcones possess a broad spectrum of biological activities including antioxidative, antibacterial, antihelmintic, amoebicidal, antiulcer, antiviral, insecticidal, antiprotozoal, anticancer, cytotoxic and immunosuppressive. Changes in their structure have offered a high degree of diversity that has proven useful for the development of new medicinal agents having improved potency and lesser toxicity and good pharmacological actions. In this study we’re specifically focusing on the the anti-oxidant activity of chalcone by Synthesizing a suitable chalcone derivative moiety and evaluating for in-vitro anti- Oxidant activity by DPPH Assay and Spectral Studies such as FTIR and UV Spectroscopy. Objectives:  To synthesize chalcone and its derivatives  To evaluate anti-Oxidant activity of chalcone and its derivatives  To Conduct Spectral Studies of chalcone and its derivatives

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