Abstract

HOW TO DEAL WITH PHEOCHROMOCYTOMA IN 2022

Mohamed El Minaoui*, Safae Ammouri, Abdelaziz El Gdaouni and Imad Ziouziou

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Abstract

Pheochromocytomas and paragangliomas are rare neuroendocrine tumors associated with fairly high morbidity and mortality, especially in complicated forms. If hypertension is the often-revealing clinical manifestation, clinical presentations remain polymorphic and the diagnosis is essentially based on the biological assay of catecholamine derivatives associated with morphological and functional radiological examinations. Computed tomography and magnetic resonance are very sensitive to localize these tumors, and functional tests are useful, especially in metastatic and multifocal disease case suspicion. More than 30% of patients have a genetic predisposition with many genes that are involved especially in its familial forms.

Keywords: Pheochromocytoma; Paraganglioma; Catecholamines; Genetic predisposition.