Abstract

CLINICAL RISK FACTORS ASSOCIATED WITH MULTIDRUGRESISTANT TUBERCULOSIS IN BANGLADESH

Albert Sanjib Mondol, Xiaoliang Yuan, Jianrong Zhou, Henry Sandip Mondol, Jarin

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Abstract

Background: Multidrug-resistant tuberculosis (MDR-TB) is a solemn barrier to successful TB control. Even though taken as a whole decreasing incidence and mortality rate for tuberculosis (TB), multidrug resistance tuberculosis (MDR-TB) continues to be a severe warning to the current global tuberculosis control effort. Objective: The aim of this study was to observe the clinical risk factors associated with MDR-TB in Bangladesh. Materials and Method: Based on selective purpose, the sample size was 305. All the patients with MDRTB were included. Results: Regarding age distribution it was found that majority (33.1%) were in the age group of 50+ years, 67.21% were male with 15001-30000 BDT as monthly family income (67.9%) and lived in rural area (83.28%). Majority (52.1%) smoked for >16 years, did not use sanitary latrine (53.8%) and illiterate (77.4%). It was revealed that most (59.7%) were suffering from TB for 6 months with pulmonary TB (90.2%). Majority (89.8%) investigated sputum, 40.3% took drug for the same duration with irregular treatment (82.3%) and laps their treatment after 6 months (70.8%) and finally failed their treatment after 8 months. Around 96.7% used 1st line drug, 94.8% received 2nd line treatment pattern. The relationship between age, weight in Kg, sex of the respondents and type of TB suffering from of the respondents was found statistically significant (p

Keywords: MDR-TB, Risk factors, Bangladesh.