Abstract

EFFECT OF BOTH ANALGESIC & ANTI- INFLAMMATORY ACTIVITY OF BUTEA FRONDOSA LINN LEAVES ON SWISS ALBINO RAT

Parul Rai*, Dr. Rajeev Shukla and Diksha Singh

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Abstract

A variety of active constituents with wide range of pharmacological actions have been reported with Butea frondosa linn. The present study was undertaken to assess analgesic and anti-inflammatory properties of its leaf extracts. Dried leaves were ethanol. Extract were evaluated for analgesic activity through, tail flick, tail immersion, and writhing assay tests at doses of 50, 100, and 200 mg/kg using Swiss albino rat. On the other hand, anti-inflammatory assay was performed by carrageenan induced paw edema of ethanol extract at 100 and 200 mg doses in Wistar albino rat. Diclofenac sodium and indomethacin were employed as a standard for analgesic and anti-inflammatory studies, respectively. Our present study demonstrated that Butea frondosa linn bears significant analgesic and anti-inflammatory activities in those models.

Keywords: Butea frondosa, Butea monosperma, Flame of forest, Pharmacology, Palash, Antiinflammatory, Analgesic, Pain, inflammation.