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Abstract

CHRONOTHERAPEUTIC DRUG DELIVERY SYSTEM: A NOVEL APPROACH

Sachin Laxman Munde* and Dr. Bindiya Chauhan

Abstract

Coordination of biological rhythms with medical treatment is called chronotherapy. Chronotherapy considers a person’s biological rhythms in determining the timing and amount of medication to optimize a drug’s desired effects and minimize the undesired ones. Study of influence of biological rhythm on the effects of medication is known as chronopharmacology while the science of study of biological rhythms is known as chronobiology. With the understanding of biological time keeping it since that these rhythms must affect how the body responds to drugs administered over the course of the day. Appropriate timing of administration can improve efficacy and diminish toxicity. Chronotherapy is relevant when the risk or intensity of the symptoms of disease vary with time as in the case of allergic rhinitis, arthritis, asthma, myocardial infarction, congestive heart failure, stroke and peptic ulcer disease.

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