Abstract

A CLINICAL STUDY TO EVALUATE THE EFFECT OF KUSHMANDA RASAYANA IN CHITTODVEGA W.S.R TO GENERALISED ANXIETY DISORDER

Ravichandra*, Shrilatha Kamath T. and Dhaneshwari H. A.

Abstract

Background: Manas has two main doshas: rajas and tamas. When there is an imbalance, it causes many manasika roga, one of which is chittodvega. Generalized Anxiety Disorder is one of the commonest psychiatric disorders in general population. Characterized by excessive or unrealistic anxiety about two or more aspect of life (work, social relationships, financial matters etc.), often accompanied by symptoms such as palpitations, shortness of breath or other somatic symptoms. Chittodvega symptoms are similar to those of Generalized Anxiety Disorder. Objective: To evaluate the therapeutic effect of Kushmanda Rasayana in Generalized Anxiety Disorder/ Chittodvega. To assess the quality of life in patients diagnosed with GAD. Methodology: An open label clinical study with pre-test and post-test design. 20 subjects with diagnostic criteria of Generalized Anxiety Disorder (GAD) were selected from OPD and IPD of Sri Dharmasthala Manjunatheshwara Ayurvedic Hospital, Udupi, Karnataka, India. The subjects were administered with Kushmanda Rasayana 12gm OD before breakfast with warm water for 30 days. The outcome measures were assessed using Hamilton’s Anxiety Rating Scale, GAD 7 Scale, and WHO Quality Of Life (WHOQOL) Scale. The assessment is done before treatment i.e. 0th day, after treatment i.e. 30th day and follow up on 60th day. The subjective parameters were analyzed statistically using Wilcoxon Signed Rank test and objective parameters like blood pressure and pulse rate were analyzed using Paired t test. Results: The results obtained were statistically significant in the parameters like Hamilton’s Anxiety Rating Scale, GAD 7 Scale, and WHO Quality Of Life (WHOQOL) Scale with P value < 0.001. Conclusion: Kushmanda Rasayana was effective in reducing symptoms of Chittodvega/Generalized Anxiety Disorder. The efficacy of the medication has been proved with the statistical analysis of the parameters.

Keywords: Chittodvega, Generalized Anxiety Disorder, Kushmanda Rasayana.