Abstract

PRESCRIBING PATTERN OF PROTON PUMP INHIBITORS IN A TERTIARY CARE HOSPITAL

Keziah Rachel Abraham*, Mahesh N. M., Irin Sara Sam, Naveendhran G., Amal Jishnu and Renoy Philip

Abstract

Background: Proton pump inhibitors are the class of drugs that is used indiscriminately, despite the increased reports of adverse events. Objective: To analyse the prescribing pattern of Proton Pump Inhibitors (PPI’s) in tertiary care hospital and to assess the drug interactions of PPI’s with co-prescribed medications. Method: A prospective observational study was conducted in 150 patients admitted in Aster CMI hospital, Hebbal, Bangalore for a period of 6 months. Result: A Total of 150 inpatients included and analysed, among them 56% were male and 44% were female. Majority of the patients were under monotherapy (98.6%) and mostly prescribed PPI was pantoprazole (98%) on both admission and discharge. Most of the PPI prescribed departments were oncology (14%) and general medicine (11.3%). Antibiotics were the most commonly co-prescribed medication with PPI’s (42.6%). There was indication for PPI therapy in 27(18%) of the cases at admission and 90(60%) at discharge, mostly for acute gastroenteritis. Conclusion: PPI’s should be used more sensibly and awareness should be created among clinicians in the hospital so that appropriate use of prescriptions with PPI’s should improve quality of life.

Keywords: PPI’s - Proton Pump Inhibitors.