Abstract

METOCLOPRAMIDE RELATED SECONDARY PARKINSONISM AND DOMPERIDONE SAFETY IN PARKINSON'S DISEASE

Hemalatha B.*, Ramnath E. and Tamiljothi E.

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Abstract

Movement disorders are a prominent group of potentially treatable conditions, that occur as a result of infectious, metabolic, or neurodegenerative disease. Drug-induced movement disorders including akathisia, tardive dyskinesia, and parkinsonism may interfere with medication adherence. DIP’s exact prevalence and incidence are unclear because it is frequently unrecognized or misdiagnosed as PD. Several drugs are known to cause drug-induced movement disorders including antipsychotic drugs, antiemetics, antidepressants, cholinomimetics, anti-vertigo, calcium channel antagonists, antiepileptics, and antiarrhythmics.

Keywords: Metoclopramide, domperidone, drug-induced parkinsonism, mechanism, management.