Abstract

ANTIBACTERIAL POTENTIAL OF ARKA ROOT BARK

*Dr. Radha Kumari, Prof. Dr. Chandan Singh, Dr. Manoj Adlakha and Dr. Rajendra Prasad Purvia

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Abstract

Medicinal plants are widely used to treat infectious diseases. Infectious diseases produced by different types of micro-organism are still the leading cause of morbidity and mortality in the world today. A huge number of synthetic antimicrobial agents are available in the market. These antimicrobial agents are very effective for the treatment of related disorders. However, due to the capacity of many microbes to acquire resistance to various antimicrobial therapies, their effectiveness is limited. The majority of these antimicrobials have side effects also. As a result, infectious diseases produced by the microbes pose a severe threat to worldwide public health. So there is a great need to develop natural anti-microbial agents. With reference to many of Ayurvedic literature keen interest has been developed to work on the plant. The introduction of natural antifungal agents to treat the fungal disease will be a great mile stone for the most significant public health accomplishment. The aim of this study was to evaluate the antibacterial potential of Ethanol, Ethyl Acetate and Chloroform extracts of the root bark of Arka. In this study Ethanol, Ethyl Acetate and Chloroform extracts were prepared from Arka root bark. These extracts were tested for their antibacterial activities by using the agar well diffusion method. It was observed that three ethanol, ethyl acetate and chloroform extracts of Arka root bark inhibited the growth of Pseudomonas viridi, Bacillus cerus, and E.Coli. Antibacterial activity of the extract was comparable to that of streptomycin. In this study it was observed that the Root bark of Calotropis procera exhibit good antibacterial potential.

Keywords: Calotropis procera; antibacterial potential; ethanol, ethyl acetate and chloroform extract.