Abstract

BUCCAL PATCHES: THE GATEWAY OF MUCOADHESIVE DRUG DELIVERY – A REVIEW

Keerthana V., Shameer Mohaideen S., L.V. Vigneshwaran* and M. Senthil Kumar

.

Abstract

Over the past 20 years, there has been a lot of scientific interest in the delivery of medications through the buccal mucosa. Various conventional and complicated techniques have been developed in an effort to transport a variety of pharmaceutical substances via the buccal route. Mucoadhesive buccal patches are a type of dosage form that uses controlled release to distribute drugs over a longer period of time. These patches often assist drugs in bypassing the liver's first pass processing and entering the systemic circulation directly. This kind of drug administration technique is thought to improve a medicine's bioavailability. The nature of the mucosal tissue and the physicochemical characteristics of the polymeric formulation are just two examples of the many variables that affect a dosage form's capacity to adhere to mucous membranes. This article provides an information on buccal patches advantages, disadvantages, ideal characteristics and basic components of mucoadhesive buccal patches.

Keywords: Structure of buccal cavity, theories of bioadhesive, mechanism of bioadhesive and methods to increase drug delivery via buccal route.