Abstract

ANALYSIS OF PRESCRIPTION PATTERN OF ANTIMICROBIALS IN GENERAL MEDICINE IN A TERTIARY CARE HOSPITAL

*Aluru Sai Srilekha, Benajir Aktar, Manoj S., Dr. Mahesh N. M. and Dr. Renoy Philip

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Abstract

Background: Excessive use of antibiotics is one of the common problems in health care system. Improper or unnecessary prescribing of antibiotics leads to emergence of antimicrobial resistance. Emergence of antimicrobial resistance will result in increase in morbidity, mortality and health care costs. Preventing inappropriate antimicrobial usage can possibly prevent drug resistance. Hence optimum use of antimicrobials can cause a great impact in improving health care system. Hence the current study aims to assess the prescribing pattern of antimicrobials in in-patient department of tertiary care hospitals. Objectives  To analyse the prescription pattern of antimicrobials in department of general medicine.  To analyse which type of infections requires more number of antimicrobials.  To identify the adverse drug reactions associated with use of antimicrobials. Method: The proposed prospective study was conducted over 150 patients of General medicine department in Aster CMI hospital, Bangalore for duration of 6 months. Result: Our study results showed a total number of 185 antimicrobials from 150 in-patient prescriptions. Majority of prescriptions contain only one antibiotic. Most common type of infections for which antibiotics was prescribed were UTI (24.83%) followed by RTI (23.48%). Cephalosporins (54.83%) were the most commonly prescribed class of antimicrobials followed by penicillin+betalactamase inhibitors (18.81%). Ceftriaxone (43.5%) of third generation cephalosporins was the drug of choice in majority of cases followed by cefoperazone (29.7%). Conclusion: Out of 150 prescriptions analyzed from General Medicine department, it was observed that prescribing of antimicrobials was appropriate with one minor ADR, which was reported and resolved by implementing proper intervention, hence appropriate prescribing of antimicrobials prevents drug resistance.

Keywords: Preventing inappropriate antimicrobial usage can possibly prevent drug resistance.