Abstract

NOVEL APPROACH OF MUCOADHESIVE POLYMERS: A REVIEW

Surya N., Shalini K., L.V. Vigneshwaran* and M. Senthil Kumar

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Abstract

In order to increase the dosage form's contact and residence times with the mucous membranes, mucoadhesive polymers are employed to improve drug delivery. The process through which polymers adhere to a biological substrate, a synthetic or natural macromolecule, mucus, or an epithelial surface is known as mucoadhesion. Mucoadhesion is a process that occurs when a biological substrate adheres to a mucosal layer. The substrate with a bioadhesive polymer can aid in long-term drug delivery at a particular delivery location. Studies on mucoadhesive polymers offer a clear understanding of mucoadhesion and several variables that can influence a polymer's mucoadhesive characteristics Mucoadhesive buccal patches are made using both natural and synthetic polymers. Because mucosal membranes are highly permeable, the mucoadhesive drug delivery technology allows for fast drug uptake into the systemic circulation without having to undergo first pass metabolism.

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