Abstract

FORMULATION AND CHARACTERIZATION OF ANTI-BACTERIAL HERBAL SILVER NANOPARTICLE

*Purva Joshi and Dr. C. K. Tyagi

Abstract

Plant-based of nanoparticles has generated worldwide interest because of cost-effectiveness, eco-friendly nature and plethora of applications. In the present research work carried out antimicrobial potential of herbal silver nanoparticles of ethanolic extract of Verbascum Thapsus leaves has been investigated. Agar well diffusion method was used for determining antimicrobial activity of Verbascum Thapsus extracts. Phytochemical analysis of ethanolic extract of Verbascum Thapsus revealed the presence of tannins, saponins, steroids, alkaloids, flavonoids, and glycosides. Herbal silver nanoparticles synthesized using Verbascum Thapsus ethanolic extract, characterized by UV–Visible spectroscopy. Evaluation of the antimicrobial potential of herbal Silver Nanoparticle recorded the highest inhibitory activity against Staphylococcus Epidermidis. The results obtained indicated that the different crude extracts of Verbascum Thapsus plant as well as herbal Silver nanoparticle have a strong and effective antimicrobial potential that provide source for the development of new drug molecules of herbal origin which may be used for the welfare of humanity.

Keywords: Verbascum Thapsus, Silver nanoparticles, Antimicrobial.