Abstract

AN AYURVEDIC AND MODERN OVERVIEW OF SHARPUNKHA (TEPHROSIA PURPUREA PERS): A REVIEW ARTICLE

*Diksha Mohan Bhirad, Prachi Khaire and Shoeb Ahmed

Abstract

Tephrosia purpurea pers. is a notable plant in Ayurveda and named "Sarwa wranvishapaka" for its property to recuperate wounds. Generally, it is rehearsed for impotency, asthma, dyspepsia, hemorrhoids, syphilis gonorrhea, ailment, augmentation of kidney and spleen. It is a significant part of natural arrangements like Tephroli and Yakrifti used to fix liver issues. Different phytocompounds including pongamol, purpurin, purpurenone, tephrosin, bulnesol, tephrostachin, β-sitosterol, etc have been accounted for. Acetylcholinesterase inhibitory activity announced from this plant helps its use for the advancement of medications for Alzheimer's and dementia neurological issues. Among the known dynamic mixtures of T. purpurea, tephrostachin is answerable for antiplasmodial action, tephrosin, pongaglabol, and semiglabrin applies antiulcer action while quercetin, rutin, β-sitosterol, and lupeol are mostly liable for its mitigating and hostile to malignant growth properties. From various toxicological investigations, fixations up to 2,000 mg/kg were viewed as protected. The current survey exhaustively sums up the ethnomedicine, phytochemistry, pharmacology, and toxicology of T. purpurea. Current pharmacological examinations have shown that the plant have wound recuperating, antileishmanial, anticarcinogenic, antimicrobial, cancer prevention agent, hepatoprotective, antifertility, antispermatogenic, hostile to diarrheal, diuretic, and insecticidal properties. Further exploration on clarification of the construction work relationship among dynamic mixtures, comprehension of multi-target network pharmacology and clinical applications will strengthen its remedial potential.

Keywords: Sharpunkha, Tephrosia purpureapers, Ayurvedic aspect, Pharmacology.