Abstract

INTESTINAL PARASITIC REDUCE COVID-19

Prof. Ragaa Issa*

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Abstract

Background: The Corona virus has a wide range of clinical manifestations and severity, including some factors that contribute to an increased risk of developing severe corona, such as cardiovascular disease, obesity, chronic lung disease and diabetes. Body: Parasitedriven immunomodulatory responses may mute hyper-inflammation associated with severe COVID-19. The researchers were collected Fecal samples from 136 immunocompromised patients (52 females and 84 males), aged 2 to 69 years. Specimens were fixed with 10% formalin for 30 min (2-3 g fecal-1) and then concentrated by a formalin-ether sedimentation technique. Samples were examined as wet saline mounts and in iodine preparation for detection of protozoan oocysts, cysts, helminthic eggs and larvae. Permanent stained smears were performed for intestinal coccidian parasites by the modified Ziehl-Neelsen technique and the modified trichrome stain. Intestinal parasites were detected in 54 (39.7%) most of them (25.7%) were with diarrhea. Patients co-infected with parasites had lower odds of developing severe COVID-19, with an adjusted odds ratio (aOR) of 0.23 (95% CI 0.17–0.30; p

Keywords: COVID 19, intestinal parasites, severity infection, cardiovascular, chronic lung disease, diabetes and obesity.