Abstract

CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF ESSENTIAL OILS OF AGERATUM CONYZOIDES (ASTERACEAE) HARVESTED IN THE REGION OF THE MOUNTAIN DISTRICT IN CÔTE D'IVOIRE

Konan N’dri Séraphin, Kouamé Bosson Antoine, Traoré Lanciné*, Gooré Kouakou Serge, MamyrBékova-Békro Janat Akhanovna and Békro Yves-Alain

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Abstract

Essential oils (EO) from the organs of Ageratum conyzoides were extracted by hydrodistillation with a yield of (0.17±0.02) % for fresh flowers and (0.27±0.03)% for stems and leaves. The chemical compositions of the organs were highlighted by GC/MS. Eighteen (18) compounds corresponding to 99.98% of the total constituents were identified in the stems and leaves. It consists of hydrocarbon (1.49%) and oxygenated (0.24%) monoterpenes, hydrocarbon (3.4%) and oxygenated (0.33%) sesquiterpenes and other compounds (0.76%). The majority phytocompound is precocene I (93.76%). That of the flowers is made up of 21 compounds also representing 99.98%) of the total chemical composition. It has the same phytochemical composition as the EO of stems and leaves but the proportions are different. The major phytoconstituent is also precocene I (90.38%). The in vitro evaluation of the antioxidant activity with the radical DPPH at 0.3 mM, showed a weak antioxidant power of the essential oil extracts. The IC50 values determined are 9.78 μg/mL for the EO extract of leaves and stems and 12.5 μg/mL for that of the flowers of the species.

Keywords: Ageratum conyzoides, essential oils, Precocene I, antioxidant activity.