Abstract

A COMPREHENSIVE REVIEW ON FORMULATION, CHARACTERIZATION EVALUATION OF PHARMACOSOMES

G. Archana*, Alekhya Mekala and Rasheed Shaik

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Abstract

Novel vesicular drug delivery devices called pharmacosomes are used. They provide a potential substitute for traditional vesicles. The amphiphilic phospholipid complexes of medicines with active hydrogen that bind to phospholipids are known as pharmacosomes. Pharmacosomes, like other vesicular systems, offer an effective way to transport medication directly to the infection site, reducing drug toxicity without causing any negative side effects. Additionally, they lower the cost of treatment by increasing drug bioavailability, particularly in the case of poorly soluble medicines. This strategy as a medication delivery system unquestionably guarantees a dependable, secure, targeted, and exact drug delivery mechanism. In addition to lowering therapy costs, drug leakage and toxicity, increasing the bioavailability of poorly soluble medications, and having restorative benefits, they aid in the regulated release of pharmaceuticals at the site of action. They are often made by hand-shaking and injecting ether. Different aspects of the pharmacosomes, such as size, surface shape, and in vitro release rate, have been assessed. This article examines pharmacosomes' potential as targeted, regulated drug delivery systems and emphasizes their manufacturing and characterization processes.

Keywords: Amphiphilic, Pharmacosomes, biosomes, targeted drug delivery system, phospholipids, bioavailability.