Abstract

NANOPARTICLES: A COMPLETE REVIEW

M. V. Sudharani*, Gugulothu Harish Chandra Naik, Pedda Babu Siva Reddy, Amidala Vineeth

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Abstract

This review is provided a detailed overview of the synthesis, properties, application and toxicities of nanoparticles exist in different forms. The word nanoparticles come from the Greek word nanus which means dwarf or very small. Nanoparticles (NPs) are the novel invention of modem science in which drug is surrounded by a polymeric membrane where the drugs are dissolved, entrapped, adsorbed, attached and/or encapsulated into or onto a Nano-particulate matrix. They can be classified into different classes based on their properties, shape, nanoparticles have unique physical and chemical properties due to their high surface area and nanoscale size. The development of Nanotechnologies is important in terms of diagnosis, treatment, and prevention of disease. Nanoparticles can be prepared by using the various methods such as Emulsion-Solvent Evaporation Method, Double Emulsion and Evaporation Method, Salting Out Method, Emulsions Diffusion Method, Solvent Displacement/Precipitation method, Polymerization method and Coacervation or ionic gelation method.

Keywords: Nanoparticles*, Modern Drug Delivery, Preparation, Characterization, Applications.