Abstract

ANTIFUNGAL POTENTIAL OF DALBERGIA SISSOO LEAF

*Dr. Jwala Verma, Prof. Dr. Chandan Singh, Dr. Rajendra Prasad Purvia and Dr. Manoj Kumar adlakha

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Abstract

Infectious disorders are frequently treated with medicinal plants. Infectious diseases caused by various microorganisms continue to be the main cause of morbidity and mortality worldwide. There is a tonne of synthetic antifungal substances on the market. The treatment of associated illnesses can be done extremely well with these antimicrobial drugs. However, their usefulness is constrained because many microorganisms are able to develop resistance to different antimicrobial medicines. Most of these antibiotics also have negative effects. Therefore, the infectious diseases caused by the bacteria constitute a serious threat to public health around the world. Therefore, the demand for developing natural anti-microbial drugs is considerable. With reference to various pieces of Ayurvedic literature, a strong desire to work on the plant. The most important public health achievement will be the introduction of natural antifungal medications to treat the fungal disease. This study's objective was to assess the antifungal potential of methanol and aqueous extracts of Dalbergia sissoo leaf material. Dalbergia sissoo leaves were processed into aqueous and methanolic extracts for this study. The agar well diffusion method was used to examine these extracts' antifungal properties. Dalbergia sissoo leaves were found to suppress the growth of Trichophyton rubrum, Epidermophyton floccusum, and Microsporum canis in both aqueous and methanolic extracts. The extract's antifungal activity was on par with that of fluconazole. In this investigation, it was found that Dalbergia sissoo leaves have strong antifungal capability.

Keywords: Dalbergia sissoo; antifungal capability; aqueous and methanolic extract.