Abstract

DETECTION OF CIRCULATING VACCINE DERIVED POLIO VIRUS- 2

Amena Kausar*, N. Kavya, Bubai Bhowmik, Dr. Sd. Abdul Jabbar Basha and M. Rajini

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Abstract

This article review is related to circulating vaccine derived polio virus type 2 (cVDPV). In general a vaccine is a substance that stimulates antibodies and boost immunity in an individual. Circulating vaccine derived poliovirus -2 is a well documented strain of poliovirus mutated from the strain of oral polio vaccine (OPV). Circulating vaccine derived polio virus-2 is the vaccine that is able to circulate for a prolonged period of time uninterrupted that can mutate and reacquire neurovirulence in a course of 12- 18 months. Episodes of circulating vaccine derived poliovirus are rare. Over the past ten years, a period during which more than ten billon doses of oral polio vaccine were given worldwide – cVDPV outbreaks resulted in fewer than 800 cases. It works by infecting cells in the gut with weakened poliovirus thereby enhancing the immunity to polio without the risk of paralysis posed by real disease. Oral Polio Vaccine is known to retain its potency over a long period if stored at -20^o C or below.

Keywords: Circulating Vaccine Derived Poliovirus-2.