Abstract

NANOPARTICLES TARGETING COLORECTAL CANCER: A REVIEW

Ashok Thulluru, Ijaz Sheik*, M. Varun, P. Esthe, R. Rani, K. Viswaja and P. Roja Naveena

Abstract

Despite great advancements in therapy, colorectal cancer (CRC) still causes major morbidity and death and is incredibly common around the world. One of the most promising approaches to treating cancer now involves the use of nanoparticles as a medication delivery mechanism. Targeted nanoparticles may take use of chemicals that are differently expressed on tumour cell surfaces to deliver cytotoxic medications to the tumour effectively. In a number of recent studies, different compounds have been used as ligands on the surfaces of nanoparticles to engage with tumour cells and facilitate the delivery of anticancer medicines. We address the prospective use of ligands and cellular targets in possible techniques for the treatment of CRCs and describe new developments in targeted nanoparticles against CRC in this article.

Keywords: CRC, Targeted nanoparticles, Chemotherapy, ligands, stimulation.