Abstract

A SHORT REVIEW ON RECENT APPROCHES IN TARGETED ON DRUG DILVAIRY SYSTEM (TDDS)

*Satish D. Mali, Tejas R. Jadhav, Dnyaneshwar S. Gawale, Dhananjay D. Chaudhari and Jayesh A. Patil

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Abstract

Targeted drug delivery is an advanced method of delivering drugs to patients in such a targeted order that increases the concentration of the delivered drug only on the body part of interest (organs/tissues/cells), which in turn improves the effectiveness of the treatment while reducing side effects of drug administration. Basically, drug targeting should help the drug molecule to preferentially reach the desired site. The inherent advantage of this technique results in the administration of the required drug with its reduced dose and reduced side effect. This inherent advantage of a targeted drug delivery system is also strongly recognized by research and development in the clinical and pharmaceutical fields as the backbone of therapeutics and diagnostics. Various drug carriers that can be used in this advanced delivery system are soluble polymers, biodegradable microsphere polymers (synthetic and natural), neutrophils, fibroblasts, artificial cells, lipoproteins, liposomes, micelles, and immune micelles. The goal of a targeted drug delivery system is to prolong, localize, target, and have a protected drug interaction with the diseased.

Keywords: Drug delivery; drug carrier system; therapeutics; diagnostics; cancer.