PHYTOCHEMICAL AND PHARMACOLOGICAL INVESTIGATION OF THE CRUDE EXTRACT OF TYPHONIUM TRILOBATUM (L.) SCHOTT
Mohammad Shahriar*, Nazma Akter Tithi, Rumana Akhter, Sonia Kamal, Syeda Najah Narjish and Mohiuddin Ahmed Bhuiyan
Abstract
Typhonium trilobatum (L.) Schott of the family Aracae has been
considered as an important plant in traditional medicine practices in
Bangladesh. The aim of the present study was to evaluate the
phytochemical constituents of Typhonium trilobatum along with invitro
antioxidant activity, in-vitro thrombolytic and membrane
stabilizing activities, in-vivo anti-spasmodic activity, in-vivo antidepressant
activity and acute toxicity were investigated. Standard
qualitative chemical tests were performed as phytochemical screening
and the presence of flavonoids, phenols, and alkaloids was detected in
various parts of the plant. Six different assays were performed to
evaluate antioxidant activity and the leaf extracts showed good
potential. The presence of flavonoid and phenolic contents was remarkable in the ethanolic
leaf extract of the plant. Methanol (% clot lysis 30.15%) and chloroform (% clot lysis
22.64%) extracts of leaves of the plant showed significant (p
Keywords: Typhonium trilobatum, Membrane stabilizing, in-vitro antioxidant activity, GI Motility, Acute Toxicity.
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