Abstract

EVALUATION OF ANTI-INFLAMMATORY POTENTIAL IN POLYHERBAL LEPAGUTI FORMULATION CONTAINING ANTIDESMA MONTANUM BLUME LEAVES USING IN-VITRO MODEL

Shilpashree V. K., Shravan B. K.*, Shrikanth Nayak, Apeksha, Megha, Preethi Seema Lobo and Dr. Ravikumar Nayak

Abstract

Antidesma montanum Blume is a folklore plant known for its antiinflammatory property. Traditional practitioners use the leaves of this plant to cure lumbar pain, arthritis in humans, and inflammation of body parts. The present work is related to the preparation of polyherbal Lepaguti containing leaves of Antidesma, Mustard, Cumin, and Pepper and its organoleptic, physicochemical, and phytochemical evaluation. The main objective of this study is to screen the anti-inflammatory activity of the developed formulation using an in-vitro model, particularly by inhibition of protein denaturation assay. The experiments were performed according to standard protocols. The data obtained from the present study shows that polyherbal Lepaguti has significant anti-inflammatory activity and it supports the folklore therapeutic claim in treating inflammatory conditions.

Keywords: Polyherbal Lepaguti, Antidesma montanum, Inflammation, Evaluation, Invitro anti-inflammatory screening.