FORMULATION AND EVALUATION OF AN ANTIFUNGAL DRUG FLUCONAZOLE AS EMULGEL USING EUCALYPTUS OIL
*Bhawani Gautam, Dr. Shailesh Sharma, Gurpreet Kaur, Ashwani Kumar, Sahukar and Kapil Jangir
Abstract
Emulgel is a mixture of two independently mixed solutions, followed
by the incorporation of hydrogel and emulsion. But when it comes to
wet pharmaceuticals, gels have a structural restriction, yet the
medicinal constituent can take advantage first of the gel's special
characteristics. The active ingredient known as emulgel was created
while gel and emulsion were being used together. Since 2000’s, many
innovative techniques in polymeric materials would be used for the
creation of aesthetic products with immediate links to the epidermis
like an infection site for assessment and therapy. Both anionic and
cationic molecules are blocked by the arrangement of polar keratinized
cells in the non-polar tight junction layer. The use of such nanosolids
in cosmetic and pharmaceutical remedies has surged because of
semisolid preparation. Hydrogel has the ability to dissolve and
transform the potential of those kinds of molecules. It reduces the risk
of cross-contamination, permitting the production of solid lipids and
cosmetics. Simultaneously, the water-soluble phase's viscosity was boosted. The addition of a
rheological thickener in liquid media thus transforms a conventional emulsion into an
emulgel. Compounds exhibited in various configurations will enhance the occurrence of
exceptional orthodox and growing of new blood vessels network in complex ways. Emulgels are now widely regarded as a more effective cutaneous medication delivery technique than the current dose form model. Emulgels can be used in pain relievers and fungal medications.
Keywords: Emulgel, Aesthatic products, Pain relievers, Fungal medications, Fluconazole, Polymeric materials.
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