Abstract

FORMULATION AND EVALUATION OF AN ANTIFUNGAL DRUG FLUCONAZOLE AS EMULGEL USING EUCALYPTUS OIL

*Bhawani Gautam, Dr. Shailesh Sharma, Gurpreet Kaur, Ashwani Kumar, Sahukar and Kapil Jangir

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Abstract

Emulgel is a mixture of two independently mixed solutions, followed by the incorporation of hydrogel and emulsion. But when it comes to wet pharmaceuticals, gels have a structural restriction, yet the medicinal constituent can take advantage first of the gel's special characteristics. The active ingredient known as emulgel was created while gel and emulsion were being used together. Since 2000’s, many innovative techniques in polymeric materials would be used for the creation of aesthetic products with immediate links to the epidermis like an infection site for assessment and therapy. Both anionic and cationic molecules are blocked by the arrangement of polar keratinized cells in the non-polar tight junction layer. The use of such nanosolids in cosmetic and pharmaceutical remedies has surged because of semisolid preparation. Hydrogel has the ability to dissolve and transform the potential of those kinds of molecules. It reduces the risk of cross-contamination, permitting the production of solid lipids and cosmetics. Simultaneously, the water-soluble phase's viscosity was boosted. The addition of a rheological thickener in liquid media thus transforms a conventional emulsion into an emulgel. Compounds exhibited in various configurations will enhance the occurrence of exceptional orthodox and growing of new blood vessels network in complex ways. Emulgels are now widely regarded as a more effective cutaneous medication delivery technique than the current dose form model. Emulgels can be used in pain relievers and fungal medications.

Keywords: Emulgel, Aesthatic products, Pain relievers, Fungal medications, Fluconazole, Polymeric materials.