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Abstract

MICROWAVE ASSISTED SYNTHESIS: A NEW TECHNOLOGY IN DRUG DISCOVERY

Bharat Jadhav*, Pradyumna Ige, Jayshree Kokat and Rajesh Mokate

Abstract

An aiding technology for hastening the processes of drug discovery and development is microwave-assisted organic synthesis. The screening of organic drug formulas, peptide synthesis, and DNA amplification are the three main applications of microwave devices in drug research. Researchers working on drug discovery and development processes like high-speed combinatorial and medicinal chemistry have found the features of microwave-assisted organic synthesis technology, including time reduction for a chemical reaction, instantaneous and uniform heating, carrying out solvent-free reactions, and the ability to conduct parallel chemical reactions, to be a gold mine. The creation of comparatively sustainable and environmentally friendly protocols for the synthesis of pharmaceuticals is the outcome of microwave-assisted organic synthesis in aqueous medium. Medical chemistry and biology have various uses for microwave-assisted synthesis when done under regulated circumstances. Pharmaceutical investigation this method has had an impact on a number of organic synthesis-related drug development fields. Pharmaceutical companies have utilized it for target identification, screening, pharmacokinetics, producing chemical libraries, and peptide synthesis.

Keywords: Green chemistry, Microwave synthesis, Drug development.


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