Abstract

BIOADHESIVE MICROSPHERES: A REVIEW ON PREPARATION AND IN-VITRO CHARACTERIZATION

Pawan Chaware*, Sanjay Sharma, Anil Bhandari, Akanksha Garud, Navneet Garud

Abstract

Microspheres have been widely accepted as a means to achieve an oral and parenteral controlled release drug delivery system. Mucoadhesion is a topic of great interest in drug delivery system. Several researchers have worked on different polymers, using different methods for the preparation of microspheres. In recent years mucoadhesive microspheres have been developed for oral, buccal, rectal, ocular, vaginal routes. The present review focuses on the methods of preparation of microspheres and the in-vitro characterization details of the prepared microspheric formulations along with their applications.

Keywords: Microsphere, mucoadhesion, method of preparation, invitro evaluation.