Abstract

CROSS- SECTIONAL STUDY OF HEPATITIS E VIRUS AMONG PREGNANT WOMEN ATTENDING ELDMAZIN HOSPITAL OBSTETRICS AND GYNECOLOGY, BLUE NILE STATE, SUDAN

Fatin Elzebair Siddig, Sid M. A., Salah E. I.*, Hassan Mohamed Eissa and Abdelrahim M. Abdelrazig

Abstract

Background: This study was carried out during the period from September to December 2016. Objectives: The study aimed was to. 1- detect IgM of hepatitis E virus in pregnant women using ICT. 2- detect IgM and IgG of HEV antibodies in patient’s serum using ELISA in Eldamazin, Blue Nile State, Sudan. Material and Methods: All serum samples were analyzed for HEV IgM rapid test using Immuno chromatographic Test (ICT) (HALOGEN) and specific anti-HEV IgM and IgG using enzymelinked immune-sorbent assay (ELISA) (DRG Instrument GmbH, - Germany). Results: 181samples negative in both ICT and ELISA(IgM),11 samples positive in both ICT and ELISA while 1 sample was negative by ICT found positive by ELISA, and 3 samples positive by ICT was found negative by ELISA, the result highly significant at 1% level.

Keywords: hepatitis E virus (HEV), IgG and IgM.