Abstract

REVIEW ON NIOSOMES AS A NOVEL DRUG DELIVERY SYSTEM

Dhabale P.*, Bavage S. B., Ingle P. V. and Patel A. C.

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Abstract

Niosome are non-ionic surfactant vesicles obtained by hydrating mixture of cholesterol and nonionic surfactants. It can be used as carriers of amphiphilic and lipophilic drug. In Niosome drug delivery system, the medication is encapsulated in a vesicle. Niosome are biodegradable, biocompatible non-immunogenic and exhibit flexibility in their structural characterization. The main object of this review the application of Niosome technology is used to treat a number of diseases, Niosome have great opportunity in research and beneficial for researcher and pharma industries. Niosome appears to be a well preferred drug delivery system over liposome as Niosome being stable and economic. Also Niosome have good drug delivery potential for targeted delivery of anticancer, anti-infective agents. Drug delivery potential of Niosome can enhances by using novel drug delivery concepts like proniosomes, discomes and asp some. Niosomes also serve better aid in diagnostic imaging and as a vaccine adjuvant. Thus these areas need further exploration and research so as to bring out or to make for commercial available Niosome preparation.

Keywords: Niosome, non-ionic, surfactant, drug intraptment, novel drug delivery system etc.