Abstract

STUDY OF DIAZEPAM DRUG RELATED WITH PHARMACOVIGILANCE

Pawar Pankaj Dattatray*, Nehe Akshay Arjun, Dhaygude Vivek Bhausaheb and Pawade Chaitanya Gorakh and Nagre Bhakti Suhash

Abstract

Diazepam is a benzodiazepine medication that is FDA approved for the management of anxiety disorders, short-term relief of anxiety symptoms, spasticity associated with upper motor neuron disorders, adjunct therapy for muscle spasms, preoperative anxiety relief, management of certain refractory epilepsy patients, and adjunct in severe recurrent convulsive seizures, and an adjunct in status epilepticus. Off-label (non-FDA approved) use for diazepam includes sedation in the ICU and short-term treatment of spasticity in children with cerebral palsy. This activity will highlight the mechanism of action, adverse event profile, approved and off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, and relevant interactions of diazepam, pertinent for interprofessional team members using diazepam for any of its intended indications.

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