A REVIEW ON CHRONOTHERAPEUTIC DRUG DELIVERY SYSTEM
Dr. R. Nepolean, M. Abirami, P. Dhanalakshmi, A. Imelda Alis Jenifer, P. Thuhilya and Dr. K. Chandramohan*
Abstract
Chronotherapeutics refers to the delivery of the drugs according to the
human circadian rhythm. Recent development in the pharmaceutical
technology has lead to the development of chronotherapeutic drug
delivery system. This system minimize the side effects of drugs and
highly effective as it is administered with a consideration of biological
rhythms of human beings. It is beneficial for the patients suffering from
diseases like cardiovascular diseases, arthritis, asthma, cancer, and
ulcer. Pulsatile drug delivery system delivers drug at the specific time
at specific site.
Keywords: chronotherapy, circadian rhythm, pulsatile drug delivery system.
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